Welcome to the University of Michigan Center of Single Molecule Analysis (CoSiMA)

In recent years a revolution has occurred in the basic sciences, which exploits novel single molecule detection and manipulation tools to track and analyze biomolecules in unprecedented detail. The goal of CoSiMA is to develop a university-wide initiative in the emerging area of single molecule technology, including single molecule spectroscopy (SMS) and imaging (SMI), laser tweezers (LT), and atomic force microscopy (AFM), to bring basic scientists, engineers, and clinical researchers together to apply this technology to the most relevant questions in medicine and nanotechnology. This initiative will thus build on the momentum established by the State's creation of the Michigan Lifescience Corridor (MLSC) Core Technology Alliance for single molecule spectroscopy at Michigan.